Disease: Achondroplasia
Source: BEFREE ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
COL10A1 Q03692 collagen type X alpha 1 chain Extracellular structure 3.0E-05 0.619 0.500
NPR2 P20594 natriuretic peptide receptor 2 Kinase 4.2E-05 0.573 0.615
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
PTH P01270 parathyroid hormone 1.2E-02 0.397 0.846
FGF2 P09038 fibroblast growth factor 2 Signaling 1.8E-02 0.383 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
POU1F1 P28069 POU class 1 homeobox 1 4.5E-02 0.548 0.654
SLC20A1 Q8WUM9 solute carrier family 20 member 1 Transporter 6.7E-02 0.582 0.577
MSX1 P28360 msh homeobox 1 Transcription factor 0.17 0.525 0.731
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
DCN P07585 decorin 0.31 0.457 0.808
FGF1 P05230 fibroblast growth factor 1 Signaling 0.44 0.507 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
PTHLH P12272 parathyroid hormone like hormone 0.81 0.453 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769