Disease: 2-3 toe syndactyly
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
ACSL4 O60488 acyl-CoA synthetase long chain family member 4 Enzyme 0.98 0.561 0.769
AGTR2 P50052 angiotensin II receptor type 2 G-protein coupled receptor 8.2E-03 0.496 0.808
BCOR Q6W2J9 BCL6 corepressor 1.00 0.471 0.808
BMP2 P12643 bone morphogenetic protein 2 Signaling 0.99 0.432 0.846
CDC45 O75419 cell division cycle 45 Nucleic acid binding 4.6E-05 0.588 0.692
CEP55 Q53EZ4 centrosomal protein 55 2.0E-12 0.534 0.731
CLCN4 P51793 chloride voltage-gated channel 4 Ion channel 1.00 0.587 0.654
DDX11 Q96FC9 DEAD/H-box helicase 11 Enzyme 2.3E-21 0.674 0.577
EBP Q15125 EBP cholestenol delta-isomerase Enzyme 0.94 0.494 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
FGFR2 P21802 fibroblast growth factor receptor 2 Kinase 1.00 0.380 0.808
HCFC1 P51610 host cell factor C1 1.00 0.601 0.692
HOXD13 P35453 homeobox D13 8.6E-03 0.483 0.808
HUWE1 Q7Z6Z7 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 Enzyme 1.00 0.534 0.769
MAN1B1 Q9UKM7 mannosidase alpha class 1B member 1 Chaperone 1.2E-08 0.606 0.577
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MED12 Q93074 mediator complex subunit 12 Transcription factor 1.00 0.476 0.769
MEIS2 O14770 Meis homeobox 2 Enzyme 1.00 0.601 0.808
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
NEDD4L Q96PU5 NEDD4 like E3 ubiquitin protein ligase Enzyme 1.00 0.573 0.731
NOG Q13253 noggin 0.89 0.518 0.731
PAK3 O75914 p21 (RAC1) activated kinase 3 Kinase 0.99 0.569 0.731
PHF6 Q8IWS0 PHD finger protein 6 Nucleic acid binding 1.00 0.581 0.692
PTCH1 Q13635 patched 1 1.00 0.398 0.885