Disease: Joint stiffness
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ATAD1 Q8NBU5 ATPase family AAA domain containing 1 1.3E-03 0.545 0.692
ATRX P46100 ATRX chromatin remodeler 1.00 0.452 0.808
CBS P0DN79 P35520 cystathionine beta-synthase Enzyme 3.1E-05 0.465 0.885
CCN6 O95389 cellular communication network factor 6 Signaling 6.2E-04 0.568 0.731
COL12A1 Q99715 collagen type XII alpha 1 chain Receptor 0.97 0.615 0.692
COL2A1 P02458 collagen type II alpha 1 chain 1.00 0.444 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC2 P18074 ERCC excision repair 2, TFIIH core complex helicase subunit Enzyme 7.1E-20 0.420 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
FKBP10 Q96AY3 FKBP prolyl isomerase 10 2.4E-06 0.606 0.538
FLNA P21333 filamin A 1.00 0.419 0.846
GUSB P08236 glucuronidase beta 4.0E-08 0.530 0.846
HGSNAT Q68CP4 heparan-alpha-glucosaminide N-acetyltransferase 6.3E-08 0.628 0.577
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
LMNA P02545 lamin A/C 1.00 0.384 0.885
MECP2 P51608 methyl-CpG binding protein 2 Epigenetic regulator 0.89 0.414 0.846
MYH3 P11055 myosin heavy chain 3 6.7E-21 0.563 0.654
PIEZO2 Q9H5I5 piezo type mechanosensitive ion channel component 2 Ion channel 8.1E-07 0.529 0.769
RAB18 Q9NP72 RAB18, member RAS oncogene family 0.91 0.582 0.692
RAB3GAP1 Q15042 RAB3 GTPase activating protein catalytic subunit 1 1.5E-07 0.566 0.692
SLC26A2 P50443 solute carrier family 26 member 2 Transporter 7.5E-07 0.553 0.692