Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | transcription factor | 0.17 | 0.251 | 0.897 |
TNF | P01375 | tumor necrosis factor | signaling molecule | 0.80 | 0.263 | 0.966 |
IL6 | P05231 | interleukin 6 | 0.34 | 0.287 | 0.966 | |
VEGFA | P15692 | vascular endothelial growth factor A | signaling molecule | 2.7E-05 | 0.298 | 0.897 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.312 | 0.931 | |
BCL2 | P10415 | BCL2, apoptosis regulator | signaling molecule | 0.57 | 0.312 | 0.862 |
IL10 | P22301 | interleukin 10 | 6.5E-03 | 0.320 | 0.931 | |
PTEN | P60484 | phosphatase and tensin homolog | hydrolase; phosphatase | 0.82 | 0.334 | 0.828 |
IFNG | P01579 | interferon gamma | 0.47 | 0.323 | 0.897 | |
EGFR | P00533 | epidermal growth factor receptor | 0.50 | 0.325 | 0.862 | |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.38 | 0.321 | 0.828 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | enzyme modulator | 9.0E-04 | 0.350 | 0.724 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | 1.00 | 0.352 | 0.793 | |
TGFB1 | P01137 | transforming growth factor beta 1 | signaling molecule | 0.17 | 0.336 | 0.931 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | kinase; transferase | 1.00 | 0.341 | 0.897 |
PTGS2 | P35354 | prostaglandin-endoperoxide synthase 2 | oxidoreductase | 1.00 | 0.338 | 0.897 |
MMP9 | P14780 | matrix metallopeptidase 9 | hydrolase; protease | 7.0E-18 | 0.339 | 0.862 |
APOE | P02649 | apolipoprotein E | 1.7E-03 | 0.352 | 0.931 | |
AKT1 | P31749 | AKT serine/threonine kinase 1 | calcium-binding protein; kinase; transfer/carrier protein; transferase | 0.98 | 0.355 | 0.862 |
CXCL8 | P10145 | C-X-C motif chemokine ligand 8 | signaling molecule | 0.342 | 0.862 | |
LMNA | P02545 | lamin A/C | 1.00 | 0.406 | 0.724 | |
HLA-DRB1 | P01911 P01912 P04229 P13760 P13761 P20039 Q29974 Q30134 Q30167 Q5Y7A7 Q95IE3 Q9GIY3 Q9TQE0 | major histocompatibility complex, class II, DR beta 1 | defense/immunity protein | 1.0E-03 | 0.347 | 0.897 |
IGF1 | P05019 | insulin like growth factor 1 | 0.29 | 0.355 | 0.828 | |
STAT3 | P40763 | signal transducer and activator of transcription 3 | nucleic acid binding; transcription factor | 1.00 | 0.358 | 0.862 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 1.2E-09 | 0.354 | 0.828 |