Disease: Heroin Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRHBP P24387 corticotropin releasing hormone binding protein Signaling 0.21 0.659 0.500
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRHR2 Q13324 corticotropin releasing hormone receptor 2 G-protein coupled receptor 8.5E-17 0.584 0.731
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GALR1 P47211 galanin receptor 1 G-protein coupled receptor 5.3E-04 0.656 0.500
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
LEP P41159 leptin 0.46 0.349 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885