Disease: Nicotine Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
ARRB2 P32121 arrestin beta 2 Enzyme modulator 0.51 0.561 0.769
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CAMK4 Q16566 calcium/calmodulin dependent protein kinase IV Kinase 0.51 0.621 0.654
CARTPT Q16568 CART prepropeptide 9.4E-02 0.576 0.692
CHRNA3 P32297 cholinergic receptor nicotinic alpha 3 subunit Ion channel 1.4E-07 0.588 0.692
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CHRNA6 Q15825 cholinergic receptor nicotinic alpha 6 subunit Ion channel 3.6E-08 0.711 0.346
CHRNB3 Q05901 cholinergic receptor nicotinic beta 3 subunit Ion channel 8.6E-06 0.705 0.308
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
GABBR1 Q9UBS5 gamma-aminobutyric acid type B receptor subunit 1 G-protein coupled receptor 1.00 0.587 0.769
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GALR1 P47211 galanin receptor 1 G-protein coupled receptor 5.3E-04 0.656 0.500
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808