Disease: Substance Dependence
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNA5 P30532 cholinergic receptor nicotinic alpha 5 subunit Ion channel 2.1E-06 0.593 0.577
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
FAM53B Q14153 family with sequence similarity 53 member B 0.86 0.716 0.423
GABRA2 P47869 gamma-aminobutyric acid type A receptor subunit alpha2 Ion channel 1.00 0.641 0.346
GABRG2 P18507 gamma-aminobutyric acid type A receptor subunit gamma2 Ion channel 0.74 0.548 0.654
GRM5 P41594 glutamate metabotropic receptor 5 G-protein coupled receptor 1.00 0.525 0.846
HTR1B P28222 5-hydroxytryptamine receptor 1B G-protein coupled receptor 0.19 0.551 0.769
LINC01854 long intergenic non-protein coding RNA 1854 0.931 0.077
LINC02052 long intergenic non-protein coding RNA 2052 0.890 0.115
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NPY P01303 neuropeptide Y Signaling 0.14 0.447 0.846
OPRD1 P41143 opioid receptor delta 1 G-protein coupled receptor 3.3E-03 0.604 0.731
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
PDYN P01213 prodynorphin Signaling 1.7E-04 0.535 0.577
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
SLC18A2 Q05940 solute carrier family 18 member A2 Transporter 7.6E-02 0.554 0.769