Disease: Anhedonia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CHRNB4 P30926 cholinergic receptor nicotinic beta 4 subunit Ion channel 0.14 0.644 0.423
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CRHR2 Q13324 corticotropin releasing hormone receptor 2 G-protein coupled receptor 8.5E-17 0.584 0.731
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
HOMER1 Q86YM7 homer scaffold protein 1 1.00 0.636 0.538
HTR1A P08908 5-hydroxytryptamine receptor 1A G-protein coupled receptor 0.20 0.522 0.846
LEP P41159 leptin 0.46 0.349 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MC4R P32245 melanocortin 4 receptor G-protein coupled receptor 9.2E-04 0.535 0.692
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
OPRK1 P41145 opioid receptor kappa 1 G-protein coupled receptor 4.1E-05 0.555 0.615
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
TPH2 Q8IWU9 tryptophan hydroxylase 2 2.5E-07 0.546 0.654