Disease: Manic
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ADRB2 P07550 adrenoceptor beta 2 G-protein coupled receptor 0.53 0.442 0.923
ANKK1 Q8NFD2 ankyrin repeat and kinase domain containing 1 Kinase 7.4E-12 0.604 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1D Q01668 calcium voltage-gated channel subunit alpha1 D Ion channel 1.00 0.582 0.577
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
DNAH8 Q96JB1 dynein axonemal heavy chain 8 Enzyme 1.1E-60 0.556 0.731
DRD1 P21728 dopamine receptor D1 G-protein coupled receptor 0.96 0.529 0.808
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GDNF P39905 glial cell derived neurotrophic factor Signaling 0.20 0.434 0.885
GRIA1 P42261 glutamate ionotropic receptor AMPA type subunit 1 Ion channel 1.00 0.570 0.577
GRK3 P35626 G protein-coupled receptor kinase 3 Kinase 0.71 0.621 0.731
GRM2 Q14416 glutamate metabotropic receptor 2 G-protein coupled receptor 0.12 0.582 0.577
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
MAOA P21397 monoamine oxidase A 1.00 0.465 0.769
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
NTNG1 Q9Y2I2 netrin G1 Enzyme modulator 0.92 0.650 0.423
NTNG2 Q96CW9 netrin G2 Enzyme modulator 1.00 0.700 0.423
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
PER2 O15055 period circadian regulator 2 Transcription factor 0.71 0.488 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923