Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
RAD51C O43502 RAD51 paralog C 6.2E-14 0.533 0.692
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
RAD51D O75771 RAD51 paralog D 1.1E-09 0.674 0.385
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
MRE11 P49959 MRE11 homolog, double strand break repair nuclease 1.3E-12 0.527 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731