Disease: Breast Cancer, Familial
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
ABRAXAS1 Q6UWZ7 abraxas 1, BRCA1 A complex subunit 5.1E-07 0.760 0.269
EMSY Q7Z589 EMSY transcriptional repressor, BRCA2 interacting 1.00 0.628 0.423
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
RAD50 Q92878 RAD50 double strand break repair protein 3.4E-27 0.556 0.808
ERCC4 Q92889 ERCC excision repair 4, endonuclease catalytic subunit Enzyme 1.4E-12 0.468 0.846
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731