Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
CDH1 P12830 cadherin 1 0.15 0.401 0.808
MIR146A microRNA 146a 0.398 0.885
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
WT1 P19544 WT1 transcription factor Nucleic acid binding 1.00 0.422 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
NOTCH3 Q9UM47 notch receptor 3 0.41 0.435 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
APRT P07741 adenine phosphoribosyltransferase 5.5E-13 0.423 0.846
VHL P40337 von Hippel-Lindau tumor suppressor Enzyme 8.0E-02 0.443 0.846
RAD51 Q06609 RAD51 recombinase 2.7E-02 0.447 0.846