Disease: Female Breast Carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRIP1 Q9BX63 BRCA1 interacting protein C-terminal helicase 1 Enzyme 6.2E-17 0.507 0.731
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
NBN O60934 nibrin Nucleic acid binding 2.2E-16 0.467 0.808
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
RAD51B O15315 RAD51 paralog B 2.1E-15 0.556 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962