| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
| ATM | Q13315 | ATM serine/threonine kinase | Kinase | 5.6E-47 | 0.374 | 0.885 |
| BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
| FANCA | O15360 | FA complementation group A | 1.6E-68 | 0.505 | 0.731 | |
| FANCC | Q00597 | FA complementation group C | 2.8E-13 | 0.507 | 0.808 | |
| KIT | P10721 | KIT proto-oncogene, receptor tyrosine kinase | Kinase | 0.98 | 0.366 | 0.808 |
| KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
| MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
| MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
| MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
| NBN | O60934 | nibrin | Nucleic acid binding | 2.2E-16 | 0.467 | 0.808 |
| NRAS | P01111 | NRAS proto-oncogene, GTPase | Enzyme modulator | 0.49 | 0.390 | 0.808 |
| PALB2 | Q86YC2 | partner and localizer of BRCA2 | 3.0E-19 | 0.485 | 0.769 | |
| PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
| RAD51 | Q06609 | RAD51 recombinase | 2.7E-02 | 0.447 | 0.846 | |
| VHL | P40337 | von Hippel-Lindau tumor suppressor | Enzyme | 8.0E-02 | 0.443 | 0.846 |