Disease: Sporadic Breast Carcinoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BARD1 Q99728 BRCA1 associated RING domain 1 1.4E-24 0.597 0.538
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRCA3 breast cancer 3 0.705 0.269
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
DHRS11 Q6UWP2 dehydrogenase/reductase 11 Enzyme 2.2E-06 0.653 0.423
EMSY Q7Z589 EMSY transcriptional repressor, BRCA2 interacting 1.00 0.628 0.423
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FANCA O15360 FA complementation group A 1.6E-68 0.505 0.731
HSD17B1 P14061 hydroxysteroid 17-beta dehydrogenase 1 Enzyme 1.3E-04 0.610 0.615
HSD17B13 Q7Z5P4 hydroxysteroid 17-beta dehydrogenase 13 2.7E-05 0.623 0.538
HSD17B7 P56937 hydroxysteroid 17-beta dehydrogenase 7 6.6E-06 0.582 0.500
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MIR146A microRNA 146a 0.398 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MSH3 P20585 mutS homolog 3 Nucleic acid binding 7.4E-31 0.474 0.769