APC |
P25054
|
APC regulator of WNT signaling pathway
|
|
1.00 |
0.373 |
0.962 |
ATM |
Q13315
|
ATM serine/threonine kinase
|
Kinase
|
5.6E-47 |
0.374 |
0.885 |
BRCA1 |
P38398
|
BRCA1 DNA repair associated
|
Enzyme
|
9.2E-29 |
0.367 |
0.923 |
BRCA2 |
P51587
|
BRCA2 DNA repair associated
|
Nucleic acid binding
|
2.4E-25 |
0.379 |
0.846 |
BRIP1 |
Q9BX63
|
BRCA1 interacting protein C-terminal helicase 1
|
Enzyme
|
6.2E-17 |
0.507 |
0.731 |
CDH1 |
P12830
|
cadherin 1
|
|
0.15 |
0.401 |
0.808 |
CDKN2A |
P42771 Q8N726
|
cyclin dependent kinase inhibitor 2A
|
|
0.39 |
0.300 |
0.885 |
CHEK2 |
O96017
|
checkpoint kinase 2
|
Kinase
|
1.2E-24 |
0.460 |
0.808 |
COL11A2 |
P13942
|
collagen type XI alpha 2 chain
|
|
0.70 |
0.435 |
0.846 |
ERBB2 |
P04626
|
erb-b2 receptor tyrosine kinase 2
|
Kinase
|
6.0E-03 |
0.328 |
0.923 |
FAP |
Q12884
|
fibroblast activation protein alpha
|
Enzyme
|
1.9E-28 |
0.496 |
0.808 |
KRAS |
P01116
|
KRAS proto-oncogene, GTPase
|
Enzyme modulator
|
7.9E-04 |
0.320 |
0.923 |
MLH1 |
P40692
|
mutL homolog 1
|
Nucleic acid binding
|
3.4E-05 |
0.399 |
0.808 |
MRC1 |
P22897
|
mannose receptor C-type 1
|
|
0.94 |
0.413 |
0.846 |
MSH2 |
P43246
|
mutS homolog 2
|
Nucleic acid binding
|
0.90 |
0.406 |
0.808 |
MSH3 |
P20585
|
mutS homolog 3
|
Nucleic acid binding
|
7.4E-31 |
0.474 |
0.769 |
MSH6 |
P52701
|
mutS homolog 6
|
Nucleic acid binding
|
3.7E-05 |
0.462 |
0.731 |
NBN |
O60934
|
nibrin
|
Nucleic acid binding
|
2.2E-16 |
0.467 |
0.808 |
PALB2 |
Q86YC2
|
partner and localizer of BRCA2
|
|
3.0E-19 |
0.485 |
0.769 |
PARP1 |
P09874
|
poly(ADP-ribose) polymerase 1
|
|
3.3E-04 |
0.389 |
0.923 |
PMS1 |
P54277
|
PMS1 homolog 1, mismatch repair system component
|
Nucleic acid binding
|
1.3E-17 |
0.569 |
0.654 |
PMS2 |
P54278
|
PMS1 homolog 2, mismatch repair system component
|
Nucleic acid binding
|
4.5E-27 |
0.484 |
0.808 |
PTEN |
P60484
|
phosphatase and tensin homolog
|
Enzyme
|
0.26 |
0.305 |
0.923 |
RAD51C |
O43502
|
RAD51 paralog C
|
|
6.2E-14 |
0.533 |
0.692 |
TP53 |
P04637
|
tumor protein p53
|
Transcription factor
|
0.53 |
0.236 |
0.962 |