Disease: High-Grade Squamous Intraepithelial Lesions
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CCR2 P41597 C-C motif chemokine receptor 2 2.3E-02 0.418 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FHIT P49789 fragile histidine triad diadenosine triphosphatase 5.7E-03 0.444 0.846
GSTM1 P09488 glutathione S-transferase mu 1 2.1E-03 0.380 0.923
H3P10 H3 histone pseudogene 10 0.350 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
MCM2 P49736 minichromosome maintenance complex component 2 Enzyme 2.6E-05 0.527 0.731
MMP1 P03956 matrix metallopeptidase 1 Enzyme 7.7E-18 0.385 0.885
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MPG P29372 N-methylpurine DNA glycosylase Enzyme 1.9E-12 0.597 0.731
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PAX1 P15863 paired box 1 0.70 0.593 0.654
PCDH10 Q9P2E7 protocadherin 10 0.89 0.582 0.769
PDXP Q96GD0 pyridoxal phosphatase Enzyme 0.26 0.533 0.731
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
SNAI1 O95863 snail family transcriptional repressor 1 0.22 0.474 0.808
TERC telomerase RNA component 0.471 0.846