Disease: Steroid Sulfatase Deficiency Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CA9 Q16790 carbonic anhydrase 9 1.3E-09 0.483 0.731
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
H3P10 H3 histone pseudogene 10 0.350 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRT20 P35900 keratin 20 9.1E-11 0.388 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MS4A1 P11836 membrane spanning 4-domains A1 Receptor 5.1E-05 0.411 0.846
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
MTOR P42345 mechanistic target of rapamycin kinase Kinase 1.00 0.343 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NME1 P15531 NME/NM23 nucleoside diphosphate kinase 1 Kinase 3.2E-03 0.443 0.808
PECAM1 P16284 platelet and endothelial cell adhesion molecule 1 Cell adhesion 0.426 0.846