Disease: Adult Solid Neoplasm
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
ALOX15 P16050 arachidonate 15-lipoxygenase Enzyme 1.1E-23 0.502 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CHPT1 Q8WUD6 choline phosphotransferase 1 Enzyme 2.4E-04 0.474 0.846
DHDDS Q86SQ9 dehydrodolichyl diphosphate synthase subunit Enzyme 0.25 0.468 0.885
DLL4 Q9NR61 delta like canonical Notch ligand 4 1.00 0.494 0.769
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FBXW7 Q969H0 F-box and WD repeat domain containing 7 Enzyme modulator 1.00 0.465 0.808
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
IDH1 O75874 isocitrate dehydrogenase (NADP(+)) 1 2.6E-12 0.424 0.808
IDH2 P48735 isocitrate dehydrogenase (NADP(+)) 2 0.88 0.434 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
MIR21 microRNA 21 0.363 0.846
NR3C1 P04150 nuclear receptor subfamily 3 group C member 1 Nuclear receptor 0.97 0.393 0.885
PARP1 P09874 poly(ADP-ribose) polymerase 1 3.3E-04 0.389 0.923