Disease: HER2-positive carcinoma of breast
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
ABCC3 O15438 ATP binding cassette subfamily C member 3 Transporter 1.2E-26 0.517 0.769
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
ATF4 P18848 activating transcription factor 4 1.6E-02 0.507 0.769
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CD24 P25063 CD24 molecule 0.472 0.769
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
COL11A2 P13942 collagen type XI alpha 2 chain 0.70 0.435 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPHB2 P29323 EPH receptor B2 Kinase 1.00 0.374 0.846
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769
FOXO3 O43524 forkhead box O3 0.99 0.431 0.808
HSP90AA1 P07900 heat shock protein 90 alpha family class A member 1 Chaperone 0.86 0.411 0.923
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MAP2K1 Q02750 mitogen-activated protein kinase kinase 1 Kinase 0.90 0.439 0.846
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923