Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
NTRK2 Q16620 neurotrophic receptor tyrosine kinase 2 Kinase 1.00 0.479 0.808
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
TP63 Q9H3D4 tumor protein p63 Transcription factor 1.00 0.362 0.769
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
CCND2 P30279 cyclin D2 Enzyme modulator 0.99 0.477 0.808
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ERCC6 P0DP91 Q03468 ERCC excision repair 6, chromatin remodeling factor 5.2E-22 0.507 0.808
NTRK3 Q16288 neurotrophic receptor tyrosine kinase 3 Kinase 1.00 0.522 0.692
RAD21 O60216 RAD21 cohesin complex component 1.00 0.528 0.846
IRF1 P10914 interferon regulatory factor 1 Transcription factor 0.99 0.468 0.769
SLC22A18 Q96BI1 solute carrier family 22 member 18 Transporter 6.5E-06 0.595 0.692
RIT1 Q92963 Ras like without CAAX 1 Enzyme modulator 0.13 0.527 0.808
EPHA3 P29320 EPH receptor A3 Kinase 1.2E-05 0.497 0.692
RICTOR Q6R327 RPTOR independent companion of MTOR complex 2 1.00 0.592 0.615
MXRA5 Q9NR99 matrix remodeling associated 5 4.3E-02 0.839 0.192
CSNK2A3 Q8NEV1 casein kinase 2 alpha 3 Kinase 2.1E-10 0.821 0.077