Disease: Acanthosis Nigricans
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
SPINK5 Q9NQ38 serine peptidase inhibitor Kazal type 5 Enzyme modulator 4.8E-28 0.604 0.654
PRMT7 Q9NVM4 protein arginine methyltransferase 7 Epigenetic regulator 5.5E-15 0.674 0.538
GZMB P10144 granzyme B Enzyme 3.7E-14 0.453 0.808
SERPINF1 P36955 serpin family F member 1 Enzyme modulator 7.8E-08 0.460 0.846
NTRK1 P04629 neurotrophic receptor tyrosine kinase 1 Kinase 2.0E-06 0.422 0.808
FGFR3 P22607 fibroblast growth factor receptor 3 Kinase 1.6E-05 0.391 0.846
CYP19A1 P11511 cytochrome P450 family 19 subfamily A member 1 Enzyme 1.7E-05 0.410 0.885
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
POMC P01189 proopiomelanocortin 1.2E-04 0.356 0.846
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
CLDN1 O95832 claudin 1 Cell-cell junction 1.0E-03 0.481 0.808
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
PNPLA2 Q96AD5 patatin like phospholipase domain containing 2 Enzyme 4.1E-03 0.511 0.846
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
LEP P41159 leptin 0.46 0.349 0.846
AKT2 P31751 AKT serine/threonine kinase 2 Kinase 0.64 0.474 0.769
TGFA P01135 transforming growth factor alpha Signaling 0.72 0.432 0.885
KRT18 P05783 keratin 18 0.73 0.530 0.692
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
CRK P46108 CRK proto-oncogene, adaptor protein 0.96 0.394 0.923