Disease: Nephrolithiasis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
UOX urate oxidase (pseudogene) 0.711 0.385
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
WDR72 Q3MJ13 WD repeat domain 72 2.7E-27 0.716 0.385
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
UMOD P07911 uromodulin 3.1E-17 0.520 0.846
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
SLC22A12 Q96S37 solute carrier family 22 member 12 Transporter 1.7E-13 0.647 0.538
CAPN1 P07384 calpain 1 Enzyme 5.9E-10 0.539 0.808
SLC2A9 Q9NRM0 solute carrier family 2 member 9 Transporter 6.9E-10 0.619 0.731
LCN2 P80188 lipocalin 2 Enzyme 1.1E-09 0.405 0.885
KCNQ1 P51787 potassium voltage-gated channel subfamily Q member 1 Ion channel 4.5E-08 0.485 0.769
SLC2A6 Q9UGQ3 solute carrier family 2 member 6 Transporter 6.7E-06 0.674 0.538
SLC37A4 O43826 solute carrier family 37 member 4 Transporter 1.7E-05 0.617 0.654
G6PC P35575 glucose-6-phosphatase catalytic subunit 1.8E-05 0.560 0.692
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CLDN16 Q9Y5I7 claudin 16 Cell-cell junction 2.5E-02 0.647 0.538
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TNFRSF11B O00300 TNF receptor superfamily member 11b 0.16 0.422 0.808
IL6 P05231 interleukin 6 0.32 0.248 0.962
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
ALB P02768 albumin Transporter 0.64 0.317 0.962
GNAS O95467 P63092 P84996 Q5JWF2 GNAS complex locus Enzyme modulator 0.68 0.420 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962