Disease: Hypercholesterolemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALMS1 Q8TCU4 ALMS1 centrosome and basal body associated protein 4.5E-60 0.559 0.808
ABCG2 Q9UNQ0 ATP binding cassette subfamily G member 2 (Junior blood group) Transporter 2.1E-32 0.419 0.885
XDH P47989 xanthine dehydrogenase Enzyme 2.6E-22 0.529 0.846
PLA2G7 Q13093 phospholipase A2 group VII Enzyme 5.3E-22 0.537 0.769
GPT P24298 glutamic--pyruvic transaminase Enzyme 3.6E-19 0.403 0.923
DECR1 Q16698 2,4-dienoyl-CoA reductase 1 Enzyme 4.5E-14 0.426 0.885
SLC5A2 P31639 solute carrier family 5 member 2 Transporter 4.9E-14 0.499 0.769
AFP P02771 alpha fetoprotein Transporter 1.1E-11 0.429 0.885
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
ADIPOQ Q15848 adiponectin, C1Q and collagen domain containing 4.6E-09 0.376 0.885
ACAT1 P24752 acetyl-CoA acetyltransferase 1 Enzyme 9.9E-08 0.538 0.692
REN P00797 renin Enzyme 2.4E-07 0.370 0.923
CYBA P13498 cytochrome b-245 alpha chain 8.9E-06 0.520 0.769
G6PC P35575 glucose-6-phosphatase catalytic subunit 1.8E-05 0.560 0.692
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
RARRES2 Q99969 retinoic acid receptor responder 2 2.7E-05 0.519 0.731
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
APOA1 P02647 apolipoprotein A1 5.5E-04 0.429 0.885
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962