Disease: Hyperlipidemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
GLB1 P16278 galactosidase beta 1 Enzyme 7.9E-10 0.448 0.808
HSPG2 P98160 heparan sulfate proteoglycan 2 Enzyme modulator 1.0E-19 0.438 0.885
HDL3 Huntington-like neurodegenerative disorder 2 0.663 0.423
ITGB2 P05107 integrin subunit beta 2 Receptor 5.1E-15 0.444 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL18 Q14116 interleukin 18 3.1E-02 0.365 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
JPH3 Q8WXH2 junctophilin 3 1.00 0.608 0.538
LRP1 Q07954 LDL receptor related protein 1 1.00 0.482 0.769
LCAT P04180 lecithin-cholesterol acyltransferase Enzyme 8.1E-02 0.588 0.654
LIPA P38571 lipase A, lysosomal acid type Enzyme 5.5E-07 0.564 0.654
LIPC P11150 lipase C, hepatic type Enzyme 3.3E-07 0.585 0.654
LPL P06858 lipoprotein lipase Enzyme 1.3E-09 0.474 0.808
LPA P08519 lipoprotein(a) Enzyme 6.6E-89 0.444 0.769
LPAL2 Q16609 lipoprotein(a) like 2, pseudogene Enzyme 0.626 0.731
LDLR P01130 low density lipoprotein receptor 9.8E-24 0.449 0.885
LDLRAP1 Q5SW96 low density lipoprotein receptor adaptor protein 1 Signaling 6.5E-06 0.641 0.538
MVP Q14764 major vault protein Nucleic acid binding 6.8E-08 0.512 0.769
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
NPC1L1 Q9UHC9 NPC1 like intracellular cholesterol transporter 1 Transporter 2.3E-20 0.656 0.423