Disease: Familial Alzheimer Disease (FAD)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CHRNB2 P17787 cholinergic receptor nicotinic beta 2 subunit Ion channel 7.3E-04 0.617 0.308
CLU P10909 clusterin 7.8E-05 0.426 0.885
CR1 P17927 complement C3b/C4b receptor 1 (Knops blood group) 1.6E-35 0.533 0.808
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
CYP46A1 Q9Y6A2 cytochrome P450 family 46 subfamily A member 1 Enzyme 0.99 0.659 0.500
DHCR24 Q15392 24-dehydrocholesterol reductase Enzyme 3.1E-02 0.498 0.769
DPYSL2 Q16555 dihydropyrimidinase like 2 Enzyme 0.99 0.585 0.692
EIF2S1 P05198 eukaryotic translation initiation factor 2 subunit alpha Nucleic acid binding 0.97 0.587 0.692
ENO1 P06733 enolase 1 Enzyme 1.9E-05 0.481 0.885
EPHA1 P21709 EPH receptor A1 Kinase 1.5E-23 0.544 0.731
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
GAPDHS O14556 glyceraldehyde-3-phosphate dehydrogenase, spermatogenic Enzyme 3.3E-05 0.780 0.154
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HLA-DRB5 Q30154 major histocompatibility complex, class II, DR beta 5 Immune response 3.6E-07 0.608 0.731
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
IDE P14735 insulin degrading enzyme Enzyme 6.6E-03 0.604 0.577
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962