Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
MTHFR P42898 methylenetetrahydrofolate reductase 3.2E-10 0.337 0.885
LEP P41159 leptin 0.46 0.349 0.846
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
HMOX1 P09601 heme oxygenase 1 9.7E-03 0.381 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MIR146A microRNA 146a 0.398 0.885
F2 P00734 coagulation factor II, thrombin Enzyme 1.1E-03 0.415 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
INSR P06213 insulin receptor Kinase 3.6E-05 0.432 0.846
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923