Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
CYP46A1 | Q9Y6A2 | cytochrome P450 family 46 subfamily A member 1 | Enzyme | 0.99 | 0.659 | 0.500 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
HMOX1 | P09601 | heme oxygenase 1 | 9.7E-03 | 0.381 | 0.923 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
MIR146A | microRNA 146a | 0.398 | 0.885 | |||
MPO | P05164 | myeloperoxidase | Enzyme | 7.1E-15 | 0.377 | 0.923 |
MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
NOS3 | P29474 | nitric oxide synthase 3 | 6.7E-07 | 0.378 | 0.885 | |
PICALM | Q13492 | phosphatidylinositol binding clathrin assembly protein | Transporter | 1.00 | 0.592 | 0.538 |
PLAU | P00749 | plasminogen activator, urokinase | Enzyme | 2.3E-06 | 0.425 | 0.923 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
RELN | P78509 | reelin | 1.00 | 0.515 | 0.731 | |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |