Disease: Neurofibrillary degeneration (morphologic abnormality)
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
ABCA7 Q8IZY2 ATP binding cassette subfamily A member 7 Transporter 2.1E-55 0.644 0.577
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
PLAU P00749 plasminogen activator, urokinase Enzyme 2.3E-06 0.425 0.923
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769