| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
| BCL2 | P10415 | BCL2 apoptosis regulator | Signaling | 0.56 | 0.291 | 0.885 |
| BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
| CHRNA7 | P36544 Q494W8 | cholinergic receptor nicotinic alpha 7 subunit | Ion channel | 4.2E-04 | 0.532 | 0.654 |
| GSK3B | P49841 | glycogen synthase kinase 3 beta | Kinase | 0.96 | 0.430 | 0.846 |
| IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
| IGF1R | P08069 | insulin like growth factor 1 receptor | Kinase | 0.97 | 0.399 | 0.885 |
| IGF2 | P01344 | insulin like growth factor 2 | 4.4E-02 | 0.390 | 0.885 | |
| IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
| INS | P01308 | insulin | 0.30 | 0.445 | 0.923 | |
| LEP | P41159 | leptin | 0.46 | 0.349 | 0.846 | |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| MTHFR | P42898 | methylenetetrahydrofolate reductase | 3.2E-10 | 0.337 | 0.885 | |
| NPY | P01303 | neuropeptide Y | Signaling | 0.14 | 0.447 | 0.846 |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
| VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |
| WWOX | Q9NZC7 | WW domain containing oxidoreductase | Enzyme | 1.2E-15 | 0.453 | 0.808 |