Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
A2M | P01023 | alpha-2-macroglobulin | Enzyme modulator | 4.5E-11 | 0.529 | 0.769 |
ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
IDE | P14735 | insulin degrading enzyme | Enzyme | 6.6E-03 | 0.604 | 0.577 |
IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |