Disease: Progressive supranuclear palsy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CLU P10909 clusterin 7.8E-05 0.426 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAOB P27338 monoamine oxidase B 1.00 0.533 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
PLCG2 P16885 phospholipase C gamma 2 Enzyme 1.00 0.588 0.808
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPI1 P60174 triosephosphate isomerase 1 Enzyme 3.0E-02 0.517 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769