| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| A2M | P01023 | alpha-2-macroglobulin | Enzyme modulator | 4.5E-11 | 0.529 | 0.769 |
| ACE | P12821 | angiotensin I converting enzyme | Enzyme | 1.0E-37 | 0.328 | 0.923 |
| ADAM10 | O14672 | ADAM metallopeptidase domain 10 | 1.00 | 0.489 | 0.846 | |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| BACE1 | P56817 | beta-secretase 1 | Enzyme | 0.88 | 0.559 | 0.769 |
| BCHE | P06276 | butyrylcholinesterase | 1.1E-13 | 0.447 | 0.923 | |
| CLU | P10909 | clusterin | 7.8E-05 | 0.426 | 0.885 | |
| CSF2 | P04141 | colony stimulating factor 2 | Signaling | 0.83 | 0.330 | 0.962 |
| CST3 | P01034 | cystatin C | 3.9E-03 | 0.436 | 0.808 | |
| F2 | P00734 | coagulation factor II, thrombin | Enzyme | 1.1E-03 | 0.415 | 0.885 |
| IDE | P14735 | insulin degrading enzyme | Enzyme | 6.6E-03 | 0.604 | 0.577 |
| IL1A | P01583 | interleukin 1 alpha | 1.6E-04 | 0.333 | 0.962 | |
| LAMC2 | Q13753 | laminin subunit gamma 2 | Enzyme modulator | 2.9E-12 | 0.389 | 0.923 |
| MME | P08473 | membrane metalloendopeptidase | Enzyme | 1.5E-18 | 0.407 | 0.808 |
| NECTIN2 | Q92692 | nectin cell adhesion molecule 2 | 0.97 | 0.575 | 0.769 | |
| PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| SORL1 | Q92673 | sortilin related receptor 1 | Transporter | 7.7E-11 | 0.582 | 0.692 |
| TTR | P02766 | transthyretin | Transporter | 0.52 | 0.423 | 0.885 |