Disease: Brain atrophy
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
AGPS O00116 alkylglycerone phosphate synthase 1.00 0.670 0.538
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BIN1 O00499 bridging integrator 1 0.78 0.550 0.692
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CD2AP Q9Y5K6 CD2 associated protein 0.23 0.558 0.731
CD33 P20138 CD33 molecule Receptor 5.7E-07 0.524 0.769
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
CLU P10909 clusterin 7.8E-05 0.426 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
MPO P05164 myeloperoxidase Enzyme 7.1E-15 0.377 0.923
PICALM Q13492 phosphatidylinositol binding clathrin assembly protein Transporter 1.00 0.592 0.538
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
SORL1 Q92673 sortilin related receptor 1 Transporter 7.7E-11 0.582 0.692
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TPP1 O14773 tripeptidyl peptidase 1 Enzyme 6.3E-07 0.551 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
TTR P02766 transthyretin Transporter 0.52 0.423 0.885
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923