Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
MMP9 | P14780 | matrix metallopeptidase 9 | Enzyme | 1.9E-17 | 0.305 | 0.923 |
BRAF | P15056 | B-Raf proto-oncogene, serine/threonine kinase | Kinase | 1.00 | 0.319 | 0.846 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
ESR1 | P03372 | estrogen receptor 1 | Nuclear receptor | 1.00 | 0.324 | 0.962 |
HIF1A | Q16665 | hypoxia inducible factor 1 subunit alpha | Transcription factor | 0.98 | 0.327 | 0.923 |
AR | P10275 | androgen receptor | Nuclear receptor | 0.99 | 0.351 | 0.846 |
FGFR1 | P11362 | fibroblast growth factor receptor 1 | Kinase | 1.00 | 0.362 | 0.885 |
PTPN11 | Q06124 | protein tyrosine phosphatase non-receptor type 11 | 1.00 | 0.385 | 0.923 | |
HRAS | P01112 | HRas proto-oncogene, GTPase | Enzyme modulator | 8.0E-02 | 0.378 | 0.885 |
NOTCH1 | P46531 | notch receptor 1 | 1.00 | 0.369 | 0.885 | |
HGF | P14210 | hepatocyte growth factor | Enzyme | 1.00 | 0.374 | 0.885 |
MET | P08581 | MET proto-oncogene, receptor tyrosine kinase | Kinase | 0.97 | 0.380 | 0.846 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
MMP3 | P08254 | matrix metallopeptidase 3 | Enzyme | 5.7E-15 | 0.408 | 0.885 |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
NOTCH2 | Q04721 | notch receptor 2 | 1.00 | 0.441 | 0.808 | |
NF1 | P21359 | neurofibromin 1 | Enzyme modulator | 0.90 | 0.440 | 0.885 |
AQP4 | P55087 | aquaporin 4 | Ion channel | 2.3E-03 | 0.456 | 0.885 |
NES | P48681 | nestin | 1.6E-06 | 0.450 | 0.808 | |
NTRK2 | Q16620 | neurotrophic receptor tyrosine kinase 2 | Kinase | 1.00 | 0.479 | 0.808 |
NDRG1 | Q92597 | N-myc downstream regulated 1 | Enzyme | 1.1E-02 | 0.488 | 0.731 |
TIMM8A | O60220 | translocase of inner mitochondrial membrane 8A | 0.65 | 0.510 | 0.846 | |
ACVR1 | Q04771 | activin A receptor type 1 | Kinase | 0.33 | 0.535 | 0.731 |
NCOA3 | Q9Y6Q9 | nuclear receptor coactivator 3 | Kinase | 0.54 | 0.522 | 0.654 |