Disease: Childhood Malignant Peripheral Nerve Sheath Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CDK4 P11802 cyclin dependent kinase 4 Kinase 6.3E-02 0.412 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
S100B P04271 S100 calcium binding protein B Calcium-binding protein 4.4E-02 0.383 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
SOX10 P56693 SRY-box transcription factor 10 0.99 0.461 0.808
SOX9 P48436 SRY-box transcription factor 9 1.00 0.419 0.846
SPP1 P10451 secreted phosphoprotein 1 2.1E-06 0.353 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962