Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
EML4 Q9HC35 EMAP like 4 4.8E-04 0.569 0.577
SMO Q99835 smoothened, frizzled class receptor G-protein coupled receptor 4.3E-07 0.489 0.731
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
FJX1 Q86VR8 four-jointed box kinase 1 0.94 0.705 0.462
DTX2 Q86UW9 deltex E3 ubiquitin ligase 2 Enzyme 2.9E-02 0.792 0.077
NRARP Q7Z6K4 NOTCH regulated ankyrin repeat protein 0.21 0.722 0.308
HES5 Q5TA89 hes family bHLH transcription factor 5 0.25 0.670 0.654
AMOT Q4VCS5 angiomotin 1.00 0.641 0.538
PTCH1 Q13635 patched 1 1.00 0.398 0.885
IQGAP2 Q13576 IQ motif containing GTPase activating protein 2 Enzyme modulator 8.5E-27 0.674 0.269
RELA Q04206 RELA proto-oncogene, NF-kB subunit Transcription factor 1.00 0.406 0.885
IL2 P60568 interleukin 2 0.48 0.336 0.885
DAPK1 P53355 death associated protein kinase 1 Kinase 1.00 0.472 0.808
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
SOX2 P48431 SRY-box transcription factor 2 Transcription factor 0.71 0.405 0.808
IQGAP1 P46940 IQ motif containing GTPase activating protein 1 Enzyme modulator 1.00 0.560 0.692
YAP1 P46937 Yes associated protein 1 Enzyme modulator 1.00 0.432 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
PON1 P27169 paraoxonase 1 9.8E-11 0.409 0.885
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846