| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
| MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
| SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
| PRNP | F7VJQ1 P04156 | prion protein | 6.3E-04 | 0.445 | 0.923 | |
| GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
| SLC6A3 | Q01959 | solute carrier family 6 member 3 | Transporter | 1.00 | 0.453 | 0.885 |
| PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
| CP | P00450 | ceruloplasmin | Enzyme | 4.2E-10 | 0.466 | 0.846 |
| C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| ITM2B | Q9Y287 | integral membrane protein 2B | 0.63 | 0.617 | 0.654 | |
| IDE | P14735 | insulin degrading enzyme | Enzyme | 6.6E-03 | 0.604 | 0.577 |
| SERPINI1 | Q99574 | serpin family I member 1 | Enzyme modulator | 2.7E-02 | 0.631 | 0.462 |
| SLC9A8 | Q9Y2E8 | solute carrier family 9 member A8 | Transporter | 2.9E-10 | 0.736 | 0.500 |
| PROS2P | protein S (beta) pseudogene | 0.780 | 0.192 |