Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CXCL8 P10145 C-X-C motif chemokine ligand 8 Signaling 2.7E-04 0.310 0.962
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
GRIN2B Q13224 glutamate ionotropic receptor NMDA type subunit 2B Ion channel 1.00 0.510 0.692
HTR2A P28223 5-hydroxytryptamine receptor 2A G-protein coupled receptor 0.51 0.473 0.846
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL1A P01583 interleukin 1 alpha 1.6E-04 0.333 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
MAPK8 P45983 mitogen-activated protein kinase 8 Kinase 1.00 0.397 0.885
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
NOS2 P35228 nitric oxide synthase 2 4.0E-15 0.364 0.923
OPRM1 P35372 opioid receptor mu 1 G-protein coupled receptor 7.9E-11 0.457 0.808
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
TACR1 P25103 tachykinin receptor 1 G-protein coupled receptor 3.8E-04 0.502 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TRPV1 Q8NER1 transient receptor potential cation channel subfamily V member 1 Ion channel 1.0E-16 0.446 0.885