Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APC | P25054 | APC regulator of WNT signaling pathway | 1.00 | 0.373 | 0.962 | |
ATOH1 | Q92858 | atonal bHLH transcription factor 1 | Enzyme | 1.8E-02 | 0.633 | 0.500 |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
CCNE1 | P24864 | cyclin E1 | Enzyme modulator | 0.97 | 0.538 | 0.731 |
CDK6 | Q00534 | cyclin dependent kinase 6 | Kinase | 0.98 | 0.471 | 0.731 |
CTNNB1 | P35222 | catenin beta 1 | 1.00 | 0.303 | 0.885 | |
DNMT1 | P26358 | DNA methyltransferase 1 | Epigenetic regulator | 1.00 | 0.406 | 0.885 |
ERBB2 | P04626 | erb-b2 receptor tyrosine kinase 2 | Kinase | 6.0E-03 | 0.328 | 0.923 |
ESR2 | Q92731 | estrogen receptor 2 | Nuclear receptor | 4.5E-08 | 0.400 | 0.923 |
GLI1 | P08151 | GLI family zinc finger 1 | 7.7E-14 | 0.431 | 0.846 | |
HIC1 | Q14526 | HIC ZBTB transcriptional repressor 1 | Transcription factor | 0.13 | 0.522 | 0.615 |
IRS2 | Q9Y4H2 | insulin receptor substrate 2 | 0.99 | 0.535 | 0.654 | |
KDM4B | O94953 | lysine demethylase 4B | Epigenetic regulator | 1.00 | 0.606 | 0.462 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
MYC | P01106 | MYC proto-oncogene, bHLH transcription factor | Transcription factor | 1.00 | 0.344 | 0.923 |
MYCL | P12524 | MYCL proto-oncogene, bHLH transcription factor | Transcription factor | 0.12 | 0.599 | 0.731 |
MYCN | P04198 | MYCN proto-oncogene, bHLH transcription factor | Transcription factor | 0.89 | 0.454 | 0.808 |
OTX2 | P32243 | orthodenticle homeobox 2 | Transcription factor | 0.92 | 0.514 | 0.808 |
PAX5 | Q02548 | paired box 5 | 1.00 | 0.487 | 0.654 | |
PDGFRA | P16234 | platelet derived growth factor receptor alpha | Kinase | 1.00 | 0.415 | 0.808 |
PIK3CG | P48736 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma | Kinase | 1.4E-06 | 0.320 | 0.885 |
PRAME | P78395 | preferentially expressed antigen in melanoma | 2.4E-07 | 0.531 | 0.577 | |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
RASSF1 | Q9NS23 | Ras association domain family member 1 | Enzyme modulator | 4.9E-06 | 0.420 | 0.808 |