Disease: Medulloblastoma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
ATOH1 Q92858 atonal bHLH transcription factor 1 Enzyme 1.8E-02 0.633 0.500
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRD2 P25440 bromodomain containing 2 Epigenetic regulator 1.00 0.450 0.808
BRD3 Q15059 bromodomain containing 3 Epigenetic regulator 0.97 0.700 0.500
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CCNE1 P24864 cyclin E1 Enzyme modulator 0.97 0.538 0.731
CDK6 Q00534 cyclin dependent kinase 6 Kinase 0.98 0.471 0.731
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
DNMT1 P26358 DNA methyltransferase 1 Epigenetic regulator 1.00 0.406 0.885
EFS O43281 embryonal Fyn-associated substrate 1.8E-08 0.597 0.615
EHMT1 Q9H9B1 euchromatic histone lysine methyltransferase 1 Epigenetic regulator 1.00 0.460 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ESR2 Q92731 estrogen receptor 2 Nuclear receptor 4.5E-08 0.400 0.923
FLI1 Q01543 Fli-1 proto-oncogene, ETS transcription factor Transcription factor 0.99 0.468 0.692
GLI1 P08151 GLI family zinc finger 1 7.7E-14 0.431 0.846
HIC1 Q14526 HIC ZBTB transcriptional repressor 1 Transcription factor 0.13 0.522 0.615
IRS2 Q9Y4H2 insulin receptor substrate 2 0.99 0.535 0.654
KAT6A Q92794 lysine acetyltransferase 6A Enzyme 1.00 0.560 0.769
KDM4B O94953 lysine demethylase 4B Epigenetic regulator 1.00 0.606 0.462
KDM4C Q9H3R0 lysine demethylase 4C 6.5E-07 0.601 0.615
L3MBTL2 Q969R5 L3MBTL histone methyl-lysine binding protein 2 Nucleic acid binding 1.0E-08 0.729 0.308
L3MBTL3 Q96JM7 L3MBTL histone methyl-lysine binding protein 3 Epigenetic regulator 1.00 0.700 0.423
MPL P40238 MPL proto-oncogene, thrombopoietin receptor Receptor 4.1E-09 0.510 0.692
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808