| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
|---|---|---|---|---|---|---|
| ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
| APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
| APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
| BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
| COMT | P21964 | catechol-O-methyltransferase | Enzyme | 1.1E-06 | 0.400 | 0.923 |
| CREB1 | P16220 | cAMP responsive element binding protein 1 | 1.00 | 0.463 | 0.885 | |
| GRIA2 | P42262 | glutamate ionotropic receptor AMPA type subunit 2 | Ion channel | 1.00 | 0.573 | 0.692 |
| GRIN2B | Q13224 | glutamate ionotropic receptor NMDA type subunit 2B | Ion channel | 1.00 | 0.510 | 0.692 |
| GRM2 | Q14416 | glutamate metabotropic receptor 2 | G-protein coupled receptor | 0.12 | 0.582 | 0.577 |
| IL1B | P01584 | interleukin 1 beta | 0.13 | 0.276 | 0.962 | |
| IL6 | P05231 | interleukin 6 | 0.32 | 0.248 | 0.962 | |
| KL | Q9UEF7 | klotho | Enzyme | 2.2E-04 | 0.448 | 0.769 |
| NFE2L2 | Q16236 | nuclear factor, erythroid 2 like 2 | Enzyme | 3.6E-03 | 0.357 | 0.885 |
| PRKAA1 | Q13131 | protein kinase AMP-activated catalytic subunit alpha 1 | Kinase | 0.14 | 0.453 | 0.846 |
| PRKAA2 | P54646 | protein kinase AMP-activated catalytic subunit alpha 2 | Kinase | 3.5E-08 | 0.456 | 0.846 |
| PRKAB1 | Q9Y478 | protein kinase AMP-activated non-catalytic subunit beta 1 | Kinase | 5.3E-03 | 0.460 | 0.846 |
| PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
| STAT3 | P40763 | signal transducer and activator of transcription 3 | Nucleic acid binding | 1.00 | 0.320 | 0.923 |
| TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
| VEGFA | P15692 | vascular endothelial growth factor A | Signaling | 2.4E-05 | 0.266 | 0.923 |