Disease: Charcot-Marie-Tooth Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
AIFM1 O95831 apoptosis inducing factor mitochondria associated 1 Enzyme 1.00 0.527 0.769
ARSA P15289 arylsulfatase A Enzyme 1.1E-11 0.448 0.923
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
DMPK Q09013 DM1 protein kinase Kinase 3.8E-02 0.603 0.692
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GARS1 P41250 glycyl-tRNA synthetase 1 Enzyme 0.31 0.623 0.500
GDAP1 Q8TB36 ganglioside induced differentiation associated protein 1 3.2E-08 0.612 0.538
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
KARS1 Q15046 lysyl-tRNA synthetase 1 Enzyme 4.2E-09 0.636 0.577
MFN1 Q8IWA4 mitofusin 1 Enzyme 2.5E-10 0.644 0.577
MFN2 O95140 mitofusin 2 Enzyme 0.99 0.471 0.846
NEFL P07196 neurofilament light 0.488 0.769
POLG P54098 DNA polymerase gamma, catalytic subunit Enzyme 2.1E-09 0.457 0.846
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
SLC25A46 Q96AG3 solute carrier family 25 member 46 Transporter 1.3E-05 0.695 0.308
SURF1 Q15526 SURF1 cytochrome c oxidase assembly factor Enzyme 1.6E-13 0.578 0.654
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
YARS2 Q9Y2Z4 tyrosyl-tRNA synthetase 2 Enzyme 3.0E-11 0.663 0.462