Disease: Leigh Disease
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC1 P33527 ATP binding cassette subfamily C member 1 Transporter 1.2E-03 0.445 0.808
ATP5F1E P56381 ATP synthase F1 subunit epsilon Transporter 8.9E-03 0.686 0.500
ATP6 P00846 ATP synthase F0 subunit 6 Transporter 0.541 0.731
ATP8 P03928 ATP synthase F0 subunit 8 Transporter 0.666 0.615
BCS1L Q9Y276 BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone 4.7E-13 0.534 0.808
C12orf65 Q9H3J6 chromosome 12 open reading frame 65 Nucleic acid binding 0.21 0.678 0.346
COQ4 Q9Y3A0 coenzyme Q4 3.4E-09 0.780 0.269
COQ8A Q8NI60 coenzyme Q8A Kinase 9.3E-11 0.674 0.385
COX10 Q12887 cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 Enzyme 8.4E-02 0.623 0.654
COX15 Q7KZN9 cytochrome c oxidase assembly homolog COX15 1.1E-13 0.638 0.538
COX4I1 P13073 cytochrome c oxidase subunit 4I1 0.39 0.691 0.500
COX5A P20674 cytochrome c oxidase subunit 5A Enzyme 0.49 0.515 0.846
COX8A P10176 cytochrome c oxidase subunit 8A Enzyme 0.12 0.400 0.846
CPOX P36551 coproporphyrinogen oxidase Enzyme 0.17 0.488 0.846
CYTB P00156 cytochrome b 0.529 0.808
FARS2 O95363 phenylalanyl-tRNA synthetase 2, mitochondrial Enzyme 9.3E-09 0.615 0.731
FOXRED1 Q96CU9 FAD dependent oxidoreductase domain containing 1 Enzyme 2.0E-16 0.633 0.462
FXN Q16595 frataxin Enzyme 0.34 0.510 0.654
GFM1 Q96RP9 G elongation factor mitochondrial 1 9.3E-13 0.623 0.692
GFM2 Q969S9 G elongation factor mitochondrial 2 Enzyme 1.5E-18 0.736 0.269
HSD17B6 O14756 hydroxysteroid 17-beta dehydrogenase 6 Enzyme 0.35 0.592 0.692
IARS2 Q9NSE4 isoleucyl-tRNA synthetase 2, mitochondrial Enzyme 8.1E-02 0.590 0.654
LRPPRC P42704 leucine rich pentatricopeptide repeat containing 2.3E-10 0.493 0.769
MARCKSL1 P49006 MARCKS like 1 1.4E-02 0.508 0.731
MTO1 Q9Y2Z2 mitochondrial tRNA translation optimization 1 7.4E-06 0.670 0.462