Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
CDKN2A | P42771 Q8N726 | cyclin dependent kinase inhibitor 2A | 0.39 | 0.300 | 0.885 | |
NOS2 | P35228 | nitric oxide synthase 2 | 4.0E-15 | 0.364 | 0.923 | |
HLA-B | P01889 | major histocompatibility complex, class I, B | 3.9E-05 | 0.379 | 0.885 | |
BRCA2 | P51587 | BRCA2 DNA repair associated | Nucleic acid binding | 2.4E-25 | 0.379 | 0.846 |
PTCH1 | Q13635 | patched 1 | 1.00 | 0.398 | 0.885 | |
CASP8 | Q14790 | caspase 8 | Enzyme | 3.7E-06 | 0.404 | 0.923 |
RAC1 | P63000 | Rac family small GTPase 1 | Enzyme modulator | 0.76 | 0.429 | 0.962 |
PTPN22 | Q9Y2R2 | protein tyrosine phosphatase non-receptor type 22 | 3.5E-21 | 0.438 | 0.846 | |
FOXP1 | Q9H334 | forkhead box P1 | 1.00 | 0.460 | 0.808 | |
CYP1B1 | Q16678 | cytochrome P450 family 1 subfamily B member 1 | Enzyme | 2.2E-05 | 0.457 | 0.769 |
TYR | P14679 | tyrosinase | Enzyme | 5.0E-32 | 0.473 | 0.808 |
TRPS1 | Q9UHF7 | transcriptional repressor GATA binding 1 | 1.00 | 0.537 | 0.769 | |
SMO | Q99835 | smoothened, frizzled class receptor | G-protein coupled receptor | 4.3E-07 | 0.489 | 0.731 |
CDKN2B-AS1 | CDKN2B antisense RNA 1 | 0.491 | 0.769 | |||
KRT5 | P13647 | keratin 5 | 0.64 | 0.512 | 0.731 | |
IRF4 | Q15306 | interferon regulatory factor 4 | Transcription factor | 0.86 | 0.491 | 0.769 |
MIR200C | microRNA 200c | 0.486 | 0.846 | |||
GPX4 | P36969 | glutathione peroxidase 4 | Enzyme | 4.8E-05 | 0.516 | 0.808 |
ILK | Q13418 | integrin linked kinase | Kinase | 3.8E-05 | 0.503 | 0.769 |
MC1R | Q01726 | melanocortin 1 receptor | G-protein coupled receptor | 8.1E-11 | 0.524 | 0.808 |
HERC2 | O95714 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 1.00 | 0.568 | 0.692 | |
LPP | Q93052 | LIM domain containing preferred translocation partner in lipoma | Enzyme modulator | 7.2E-03 | 0.543 | 0.769 |
CTSS | P25774 | cathepsin S | Enzyme | 0.34 | 0.539 | 0.731 |