Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
SERPINA1 | P01009 | serpin family A member 1 | Enzyme modulator | 6.8E-08 | 0.410 | 0.923 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
ATXN2 | Q99700 | ataxin 2 | Nucleic acid binding | 0.85 | 0.482 | 0.808 |
LPA | P08519 | lipoprotein(a) | Enzyme | 6.6E-89 | 0.444 | 0.769 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
ATXN1 | P54253 | ataxin 1 | 0.97 | 0.534 | 0.769 | |
TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 |
IGFALS | P35858 | insulin like growth factor binding protein acid labile subunit | Receptor | 5.4E-11 | 0.511 | 0.846 |
HTT | P42858 | huntingtin | 1.00 | 0.548 | 0.654 | |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
TMEM106B | Q9NUM4 | transmembrane protein 106B | 0.33 | 0.590 | 0.462 | |
TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |
ARHGAP35 | Q9NRY4 | Rho GTPase activating protein 35 | 1.00 | 0.751 | 0.269 |