Disease: Presenile dementia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR21 microRNA 21 0.363 0.846
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
MCIDAS D6RGH6 multiciliate differentiation and DNA synthesis associated cell cycle protein 1.3E-02 0.566 0.769
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
STXBP3 O00186 syntaxin binding protein 3 Transporter 5.2E-05 0.610 0.769
LAD1 O00515 ladinin 1 Cellular structure 1.8E-14 0.584 0.731
CIT O14578 citron rho-interacting serine/threonine kinase Kinase 1.00 0.555 0.692
PRKN O60260 parkin RBR E3 ubiquitin protein ligase Enzyme 6.9E-07 0.431 0.846
PSPN O60542 persephin Signaling 1.1E-04 0.608 0.769
PLA2G6 O60733 phospholipase A2 group VI Enzyme modulator 2.5E-10 0.476 0.846
REM1 O75628 RRAD and GEM like GTPase 1 5.3E-08 0.531 0.885
SNCG O76070 synuclein gamma Transporter 8.5E-04 0.550 0.615
TOMM40 O96008 translocase of outer mitochondrial membrane 40 Transporter 0.99 0.590 0.538
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SERPINA1 P01009 serpin family A member 1 Enzyme modulator 6.8E-08 0.410 0.923
SERPINA3 P01011 serpin family A member 3 Enzyme modulator 8.8E-14 0.486 0.846
A2M P01023 alpha-2-macroglobulin Enzyme modulator 4.5E-11 0.529 0.769
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
INS P01308 insulin 0.30 0.445 0.923
IGF2 P01344 insulin like growth factor 2 4.4E-02 0.390 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
TF P02787 transferrin Enzyme 4.1E-08 0.527 0.846