Disease: Mild cognitive disorder
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABI3 Q9P2A4 ABI family member 3 Enzyme modulator 5.0E-05 0.716 0.231
ACE P12821 angiotensin I converting enzyme Enzyme 1.0E-37 0.328 0.923
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
AD12 Alzheimer disease 12 0.711 0.538
AGER Q15109 advanced glycosylation end-product specific receptor Receptor 6.4E-16 0.420 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
BACE1 P56817 beta-secretase 1 Enzyme 0.88 0.559 0.769
BCHE P06276 butyrylcholinesterase 1.1E-13 0.447 0.923
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
BRAP Q7Z569 BRCA1 associated protein 3.8E-06 0.612 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CAMK2A Q9UQM7 calcium/calmodulin dependent protein kinase II alpha Kinase 1.00 0.612 0.538
CASP2 P42575 caspase 2 Enzyme 1.5E-03 0.565 0.731
CASP3 P42574 caspase 3 Enzyme 0.10 0.351 0.923
CHI3L1 P36222 chitinase 3 like 1 1.1E-05 0.419 0.885
CHRNA4 P43681 cholinergic receptor nicotinic alpha 4 subunit Ion channel 8.5E-05 0.492 0.808
CLU P10909 clusterin 7.8E-05 0.426 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CSF1R P07333 colony stimulating factor 1 receptor Kinase 0.13 0.448 0.808
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
CTSB P07858 cathepsin B Enzyme 5.9E-11 0.457 0.846
CYP2B6 P20813 cytochrome P450 family 2 subfamily B member 6 1.9E-10 0.428 0.846