Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL6 P05231 interleukin 6 0.32 0.248 0.962
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
SMUG1 Q53HV7 single-strand-selective monofunctional uracil-DNA glycosylase 1 4.5E-04 0.322 0.923
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
ABCB1 P08183 ATP binding cassette subfamily B member 1 Transporter 1.3E-05 0.344 0.885
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
MIR21 microRNA 21 0.363 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
SLC2A1 P11166 solute carrier family 2 member 1 Transporter 0.99 0.388 0.808
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
CCL5 P13501 C-C motif chemokine ligand 5 Signaling 1.8E-03 0.403 0.885
MME P08473 membrane metalloendopeptidase Enzyme 1.5E-18 0.407 0.808
TYMS P04818 thymidylate synthetase Enzyme 0.72 0.425 0.846
RASSF1 Q9NS23 Ras association domain family member 1 Enzyme modulator 4.9E-06 0.420 0.808
MKI67 P46013 marker of proliferation Ki-67 1.3E-28 0.431 0.808
MIB1 Q86YT6 mindbomb E3 ubiquitin protein ligase 1 Enzyme 3.4E-88 0.438 0.769
EIF4E P06730 eukaryotic translation initiation factor 4E Nucleic acid binding 0.94 0.448 0.846
AURKA O14965 aurora kinase A Kinase 0.87 0.475 0.731
PPP1R2C O14990 PPP1R2C family member C Enzyme modulator 0.478 0.846