Disease: Mammary Tumorigenesis
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COX2 P00403 cytochrome c oxidase subunit II Enzyme 0.352 0.962
MTCO2P12 MT-CO2 pseudogene 12 0.368 0.962
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
CHEK2 O96017 checkpoint kinase 2 Kinase 1.2E-24 0.460 0.808
MELK Q14680 maternal embryonic leucine zipper kinase Kinase 4.5E-22 0.566 0.577
PALB2 Q86YC2 partner and localizer of BRCA2 3.0E-19 0.485 0.769
ERBB3 P21860 erb-b2 receptor tyrosine kinase 3 Kinase 1.7E-15 0.448 0.808
PRL P01236 prolactin Signaling 2.9E-07 0.406 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
CAV1 Q03135 caveolin 1 Enzyme modulator 8.3E-03 0.388 0.885
MUC1 P15941 mucin 1, cell surface associated 1.9E-02 0.384 0.885
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KAT5 Q92993 lysine acetyltransferase 5 8.8E-02 0.534 0.769
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885